NFL Week 3 picks: Will the Chargers stay undefeated and the Rams winless?

Los Angeles Times NFL writer Sam Farmer examines the matchups this week. Lines according to FanDuel Sportsbook (O/U = over/under). Record last week 8-8 (.500); season 19-13 (.594). Using point spreads with the scores Farmer predicted, the record against the spread last week would have been 7-8-1 (.467); season 18-13-1 (.581). Times Pacific.

Jets linebacker Jermaine Johnson (11) is examined by the medical staff as coach Robert Saleh (right) watches. Johnson tore his Achilles.

(Stew Milne / Associated Press)

Tonight, 5:30. TV: Amazon Prime Video

Line: Jets by 6½. O/U: 38½.

Jets losing defensive end Jermaine Johnson really hurts them. The Patriots are looking much better than expected. The Jets have more playmakers, but New England keeps it closer than some might suspect.

Pick: Jets 23, Patriots 18

Under new coach Jim Harbaugh, the Chargers are 2-0 for the first time since 2012.

(Robert Gauthier / Los Angeles Times)

Sunday, 10 a.m. TV: Channel 2

Line: Steelers by 1½. O/U: 35½.

Early indications are that Jim Harbaugh has instilled a toughness in the Chargers we haven’t seen in a while. They have a balanced attack and are capable of picking up a big road win at Pittsburgh.

Pick: Chargers 20, Steelers 17

Eagles receiver A.J. Brown did not play last week because of a hamstring injury.

(Andre Penner / Associated Press)

Sunday, 10 a.m. TV: Channel 11

Line: Saints by 2½. O/U: 49½.

The Eagles are coming off a short week and a soul-crushing defeat at home. They are different with a healthy A.J. Brown. The New Orleans defense is pretty solid, and that offense is rolling.

Pick: Saints 27, Eagles 24

It has been a rough start to the season for quarterback Daniel Jones and the Giants.

(Matt Slocum / Associated Press)

Sunday, 10 a.m. TV: NFL Ticket

Line: Browns by 6½. O/U: 38½.

After an embarrassing opener, Cleveland’s defense woke up. That should be enough to handle Daniel Jones and the Giants, who looked a bit better last week but still have their issues.

Pick: Browns 24, Giants 16

Quarterback Anthony Richardson (5) and the Colts have not hit the win column yet.

(Matt Ludtke / Associated Press)

Sunday, 10 a.m. TV: NFL Ticket

Line: Colts by 1½. O/U: 43½.

Good thing for the Colts that the Bears don’t have a great ground attack because, so far, Indianapolis can’t stop the run. If the Colts don’t turn it over, they have enough to outscore an anemic offense.

Pick: Colts 21, Bears 13

The Texans have had difficulty protecting quarterback C.J. Stroud (7) so far this season.

(Eric Christian Smith / Associated Press)

Sunday, 10 a.m. TV: NFL Ticket

Line: Texans by 2½. O/U: 45½.

Brian Flores is doing a great job with that Vikings defense and getting after the quarterback. The Texans, meanwhile, could do a much better job of protecting C.J. Stroud. Minnesota is at home.

Pick: Vikings 24, Texans 20

The Broncos’ offense under coach Sean Payton has not clicked so far this season.

(Jack Dempsey / Associated Press)

Sunday, 10 a.m. TV: NFL Ticket

Line: Buccaneers by 6½. O/U: 39½.

Strange with Sean Payton as coach, but the Broncos offense looks a little stale and out of sync. Tough to cure that against a solid Tampa Bay defense, although Buccaneers are banged up.

Pick: Buccaneers 24, Broncos 16

Packers quarterback Malik Willis (2) will start against his former team in Week 3.

(Matt Ludtke / Associated Press)

Sunday, 10 a.m. TV: NFL Ticket

Line: Titans by 2½. O/U: 36½.

Packers quarterback Malik Willis faces his former team. The Packers ran decisively against Indianapolis and, although they probably won’t rack up as many yards against the Titans, can do enough to win.

Pick: Packers 23, Titans 18

Raiders quarterback Gardner Minshew (15) led an upset of the Ravens in Week 2 after trailing by 10 points.

(Terrance Williams / Associated Press)

Sunday, 1:05 p.m. TV: NFL Ticket

Line: Raiders by 5½. O/U: 40½.

Carolina’s a mess but might look a little better with Andy Dalton at quarterback. The Raiders have a very good defense, and the offense is gaining confidence in Gardner Minshew.

Pick: Raiders 27, Panthers 17

Skylar Thompson will make his first start this week in place of the injured Tua Tagovailoa.

(Lynne Sladky / Associated Press)

Sunday, 1:05 p.m. TV: NFL Ticket

Line: Seahawks by 4½. O/U: 41½.

The Seahawks have cobbled together two close wins, and this will be the best team they’ve faced. The Dolphins are a step up in competition but aren’t the same with Skylar Thompson at quarterback.

Pick: Seahawks 21, Dolphins 13

The Rams are going to suffer at receiver without injured Cooper Kupp in the lineup.

(Gina Ferazzi / Los Angeles Times)

Sunday, 1:25 p.m. TV: Channel 11

Line: 49ers by 7½. O/U: 43½.

Things are going to get worse for the injury-riddled Rams before they get better. Losing Cooper Kupp is big. They have a hard enough time with San Francisco as it is. Rams are running on fumes.

Pick: 49ers 31, Rams 17

Can quarterback Kyler Murray lead the Cardinals to their second win in a row?

(Ross D. Franklin / Associated Press)

Sunday, 1:25 p.m. TV: NFL Ticket

Line: Lions by 3. O/U: 52½.

Cardinals have put together two strong weeks and are going to be fun to watch this season. The Lions are coming off a loss, but they were their own worst enemy in Tampa Bay game. Close, but visitors prevail.

Pick: Lions 28, Cardinals 24

Cowboys linebacker Micah Parsons (11) could pose a problem for the 0-2 Ravens.

(Kyusung Gong / Associated Press)

Sunday, 1:25 p.m. TV: NFL Ticket

Line: Ravens by 1½. O/U: 48½.

Terrible start for the Ravens, and this is not an ideal opponent to end the slide. Baltimore doesn’t have great blocking tight ends, and that’s an issue against a defense with Micah Parsons.

Pick: Cowboys 27, Ravens 23

Falcons quarterback Kirk Cousins (18) led the deciding drive with less than two minutes remaining against the Eagles last week.

(Matt Rourke / Associated Press)

Sunday, 5:20 p.m. TV: Channel 4

Line: Chiefs by 3½. O/U: 46½.

The Falcons have to be floating on a cloud after that come-from-behind win at Philadelphia. They still have a lot to prove, though. The Chiefs have way too much firepower, even with Isiah Pacheco out.

Pick: Chiefs 28, Falcons 21

Josh Allen (17) and the Bills are 2-0 and the only unbeaten team in the AFC East.

(Doug Murray / Associated Press)

Monday, 4:30 p.m. TV: ESPN

Line: Bills by 4½. O/U: 45½.

Sometimes it’s addition by subtraction, and Josh Allen and the Bills are doing fine without Stefon Diggs. Jacksonville is talented and healthy, but the Jaguars can’t seem to pull it together yet.

Pick: Bills 24, Jaguars 20

Quarterback Jayden Daniels’ running ability has helped the Washington Commanders.

(Matt Slocum / Associated Press)

Monday, 5:15 p.m. TV: Channel 7

Line: Bengals by 7½. O/U: 48½.

Jayden Daniels has looked pretty solid so far, and this team isn’t going to roll over, but the Bengals are starting to click, and defensive coordinator Lou Anarumo will draw something up against the rookie.

Pick: Bengals 30, Commanders 20