The Gunners, who finished fifth last season, have enjoyed their best ever start to a league campaign, amassing 31 points from 12 games to top the table.
Defending champions Man City appear to be in ominous form sitting second while Antonio Conte’s Tottenham are third despite the questions over Spurs’ style of play.
Newcastle United, one of the richest clubs in the world following their Saudi-backed takeover last year, have only lost once this season to climb to fourth.
Manchester United are also impressing under Erik ten Hag and moved ahead of Chelsea into fifth over the weekend.
Newly-promoted Fulham and Graham Potter’s former club Brighton are seventh and eighth respectively, ahead of Liverpool who are enduring a dismal run, winning just a third of their league fixtures.
While there is still much to play for, Ferdinand is adamant that three teams will finish in the top-four, insisting he would ‘put his house’ on the outcome.
Speaking on the Vibe with Five YouTube channel, he said: ‘It will be Arsenal, Man City and Man United – they are the three teams I would put my house on now.
‘And then the fourth one I can’t pick. Newcastle could come in and take it.’
Liverpool were expected to challenge for the Premier League title after going close to the quadruple last season but a shocking run has seen the Reds slip to mid-table.
Rating Liverpool’s top-four chances after Saturday’s shock defeat to Leeds United, Klopp said: ‘That is actually not my main worry.
‘There are a lot of other worries, but of course I am not that dumb that I don’t know about distances and who is up there.
‘But we cannot qualify for the Champions League if you play as inconsistent as we do at the moment. We have to fix that and then we will see where we will end up.
‘We know everything is possible, or a lot of things are possible. But for that we have to win football games and we didn’t do that often enough yet.’
Manchester United legend Gary Neville, meanwhile, has backed his former club to make the top-four this season following their turnaround under Ten Hag.
The Red Devils lost their opening two games of the season but have largely impressed since then, winning six from eight in all competitions.
‘I think they have a great chance of finishing in the top four now. A great chance,’ Neville told Sky Sports.
‘I think there is enough around Chelsea, Liverpool, and Spurs that United will feel they can push through that bunch. I never would have thought that four or five weeks ago.’